SuppRankedTop 10 probiotics brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Probiotics Best Sellers top 100. Updated October 15, 2026.
Garden of Life is the top-selling probiotics brand on Amazon by estimated revenue, at about $4.9M/mo from 9 products in the Probiotics Best Sellers top 100. That is about 46% more than #2 Physician's CHOICE (~$3.3M/mo). The list is fragmented: the top 3 brands take about 31% of its estimated sales and the top 10 about 63%, spread across 49 brands in total. About 11% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Garden of Life14% share · best #2 | $4.9M |
| 2 | Physician's CHOICE9% share · best #1 | $3.3M |
| 3 | Align8% share · best #14 | $3M |
| 4 | Seed7% share · best #4 | $2.5M |
| 5 | Florastor7% share · best #7 | $2.3M |
| 6 | Culturelle6% share · best #5 | $2.3M |
| 7 | Lemme3% share · best #10 | $1.2M |
| 8 | Jarrow Formulas3% share · best #52 | $1.1M |
| 9 | ZBiotics3% share · best #8 | $909K |
| 10 | MaryRuth's2% share · best #23 | $853K |
The top 10, brand by brand
1. Garden of Life
~$4.9M/mo est. revenue (14% of this list) and ~168K units/mo from 9 products; best position #2. Its highest-ranked product here is Garden of Life Dr. Formulated Once Daily Women's Probiotics, 50B CFU, 30ct | 50… at #2. Overall it ranks #18 of 3,479 brands.
2. Physician's CHOICE
~$3.3M/mo est. revenue (9% of this list) and ~168K units/mo from 3 products; best position #1. Its highest-ranked product here is Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics… at #1. Overall it ranks #37 of 3,479 brands.
3. Align
~$3M/mo est. revenue (8% of this list) and ~76.6K units/mo from 9 products; best position #14. Its highest-ranked product here is Align Probiotic, Pro Formula, Probiotics for Women and Men, Probiotics for… at #14. Overall it ranks #135 of 3,479 brands.
4. Seed
~$2.5M/mo est. revenue (7% of this list) and ~42.1K units/mo from 1 product; best position #4. Its highest-ranked product here is Seed DS-01 Daily Synbiotic - Adult Probiotic + Prebiotic - 30-Days with Jar… at #4. Overall it ranks #351 of 3,479 brands.
5. Florastor
~$2.3M/mo est. revenue (7% of this list) and ~44.7K units/mo from 2 products; best position #7. Its highest-ranked product here is Florastor Probiotic for Digestive and Immune Health, 100 Capsules | Probiotics… at #7. Overall it ranks #282 of 3,479 brands.
6. Culturelle
~$2.3M/mo est. revenue (6% of this list) and ~89.6K units/mo from 6 products; best position #5. Its highest-ranked product here is Culturelle Pro Strength Probiotics for Digestive Gut Health*, 12B CFU, 60ct… at #5. Overall it ranks #107 of 3,479 brands.
7. Lemme
~$1.2M/mo est. revenue (3% of this list) and ~39.6K units/mo from 2 products; best position #10. Its highest-ranked product here is Lemme Purr Vaginal Probiotic Gummies for Women, 30-Day Supply | Balanced pH… at #10. Overall it ranks #46 of 3,479 brands.
8. Jarrow Formulas
~$1.1M/mo est. revenue (3% of this list) and ~35.5K units/mo from 3 products; best position #52. Its highest-ranked product here is Jarrow FemDophilus Probiotics, Vaginal & Urinary Tract Support, 60 Capsules… at #52. Overall it ranks #32 of 3,479 brands.
9. ZBiotics
~$909K/mo est. revenue (3% of this list) and ~25.2K units/mo from 1 product; best position #8. Its highest-ranked product here is ZBiotics Pre-Alcohol Probiotic — Drink Responsibly, for an Easier Tomorrow at #8. Overall it ranks #271 of 3,479 brands.
10. MaryRuth's
~$853K/mo est. revenue (2% of this list) and ~38.9K units/mo from 3 products; best position #23. Its highest-ranked product here is MaryRuth Organics Kids Probiotics for Digestive Health | USDA Probiotic Gummies… at #23. Overall it ranks #15 of 3,479 brands.
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Full Probiotics ranking
All 49 brands in the list, ordered by rank strength, plus the top 10 products.
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