SuppRankedTop 10 glucosamine brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Glucosamine Best Sellers top 100. Updated October 15, 2026.
Schiff is the top-selling glucosamine brand on Amazon by estimated revenue, at about $1M/mo from 4 products in the Glucosamine Best Sellers top 100. That is about the same as #2 Osteo Bi-Flex (~$1M/mo). The list is fragmented: the top 3 brands take about 24% of its estimated sales and the top 10 about 60%, spread across 51 brands in total. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Schiff8% share · best #36 | $1M |
| 2 | Osteo Bi-Flex8% share · best #3 | $1M |
| 3 | Kirkland Signature8% share · best #13 | $936K |
| 4 | Dona7% share · best #11 | $875K |
| 5 | Designs for Health7% share · best #17 | $822K |
| 6 | NOW Foods5% share · best #9 | $649K |
| 7 | Pure Encapsulations5% share · best #27 | $609K |
| 8 | GNC4% share · best #44 | $513K |
| 9 | UpWellness4% share · best #8 | $454K |
| 10 | Nature's Way4% share · best #2 | $449K |
The top 10, brand by brand
1. Schiff
~$1M/mo est. revenue (8% of this list) and ~10.3K units/mo from 4 products; best position #36. Its highest-ranked product here is Schiff Glucosamine 1500mg Plus MSM and Hyaluronic Acid, 150 tablets - Joint… at #36. Overall it ranks #1098 of 3,479 brands.
2. Osteo Bi-Flex
~$1M/mo est. revenue (8% of this list) and ~41K units/mo from 2 products; best position #3. Its highest-ranked product here is Osteo Bi-Flex One Per Day Vitamin D Supplement, 60 Coated Tablets | Improve… at #3. Overall it ranks #96 of 3,479 brands.
3. Kirkland Signature
~$936K/mo est. revenue (8% of this list) and ~27.5K units/mo from 7 products; best position #13. Its highest-ranked product here is Kirkland Signature Glucosamine with MSM, 375 Tablets at #13. Overall it ranks #186 of 3,479 brands.
4. Dona
~$875K/mo est. revenue (7% of this list) and ~18.7K units/mo from 4 products; best position #11. Its highest-ranked product here is Dona Crystalline Glucosamine Sulfate, 1500 Mg, Joint Supplement Pills for Knee… at #11. Overall it ranks #660 of 3,479 brands.
5. Designs for Health
~$822K/mo est. revenue (7% of this list) and ~9.5K units/mo from 2 products; best position #17. Its highest-ranked product here is Designs for Health IgGI Shield Powder, Intestinal Function, 30 Servings… at #17. Overall it ranks #26 of 3,479 brands.
6. NOW Foods
~$649K/mo est. revenue (5% of this list) and ~35.3K units/mo from 6 products; best position #9. Its highest-ranked product here is NOW Supplements, Vegetarian Glucosamine & MSM, w/ GreenGrown®, 240 Veg Caps at #9. Overall it ranks #1 of 3,479 brands.
7. Pure Encapsulations
~$609K/mo est. revenue (5% of this list) and ~9.2K units/mo from 3 products; best position #27. Its highest-ranked product here is Pure Encapsulations Glucosamine Sulfate 1,000 mg, 60 Capsules | Supplement for… at #27. Overall it ranks #3 of 3,479 brands.
8. GNC
~$513K/mo est. revenue (4% of this list) and ~11.2K units/mo from 4 products; best position #44. Its highest-ranked product here is GNC Triple Strength Glucosamine Chondroitin, Mobility Support, 120 Caplets… at #44. Overall it ranks #36 of 3,479 brands.
9. UpWellness
~$454K/mo est. revenue (4% of this list) and ~11.4K units/mo from 1 product; best position #8. Its highest-ranked product here is UpWellness Cartilage Revive + Joint Support Supplement, 60 Capsules | Type II… at #8. Overall it ranks #655 of 3,479 brands.
10. Nature's Way
~$449K/mo est. revenue (4% of this list) and ~30K units/mo from 1 product; best position #2. Its highest-ranked product here is Nature's Way Joint Movement Glucosamine Liquid, Chondroitin, Berry, 16 oz | MSM… at #2. Overall it ranks #12 of 3,479 brands.
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Full Glucosamine ranking
All 51 brands in the list, ordered by rank strength, plus the top 10 products.
See all Glucosamine brands →