Top 10 protein brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Protein Best Sellers top 100. Updated October 15, 2026.
Ensure is the top-selling protein brand on Amazon by estimated revenue, at about $2.5M/mo from 7 products in the Protein Best Sellers top 100. That is about the same as #2 Orgain (~$2.4M/mo). The list is fragmented: the top 3 brands take about 22% of its estimated sales and the top 10 about 51%, spread across 56 brands in total. The median list price in this top 100 is $34.99. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Ensure8% share · best #3 | $2.5M |
| 2 | Orgain8% share · best #2 | $2.4M |
| 3 | Isopure6% share · best #14 | $1.9M |
| 4 | Optimum Nutrition5% share · best #1 | $1.7M |
| 5 | Dymatize4% share · best #4 | $1.4M |
| 6 | Transparent Labs4% share · best #5 | $1.4M |
| 7 | NAKED4% share · best #6 | $1.3M |
| 8 | Nutricost4% share · best #25 | $1.2M |
| 9 | Muscle Milk4% share · best #11 | $1.1M |
| 10 | Ascent3% share · best #22 | $1M |
The top 10, brand by brand
1. Ensure
~$2.5M/mo est. revenue (8% of this list) and ~77.2K units/mo from 7 products; best position #3. Its highest-ranked product here is Ensure Max Protein Milk Chocolate Shake, 30g High Protein, 12 Pack | 30g… at #3. Overall it ranks #52 of 935 brands.
2. Orgain
~$2.4M/mo est. revenue (8% of this list) and ~80.2K units/mo from 6 products; best position #2. Its highest-ranked product here is Orgain Organic Vegan 21g Protein Powder, Vanilla Bean, 2.03 lb | Plant based… at #2. Overall it ranks #18 of 935 brands.
3. Isopure
~$1.9M/mo est. revenue (6% of this list) and ~35.3K units/mo from 3 products; best position #14. Its highest-ranked product here is Isopure Zero Carb Whey Isolate Protein Powder, Creamy Vanilla 3 LB | 25g… at #14. Overall it ranks #54 of 935 brands.
4. Optimum Nutrition
~$1.7M/mo est. revenue (5% of this list) and ~36K units/mo from 2 products; best position #1. Its highest-ranked product here is Optimum Nutrition Gold Standard Whey Protein Powder, Vanilla Ice Cream, 2LB… at #1. Overall it ranks #13 of 935 brands.
5. Dymatize
~$1.4M/mo est. revenue (4% of this list) and ~39.5K units/mo from 3 products; best position #4. Its highest-ranked product here is Dymatize ISO100 Protein Powder, 100% Whey Isolate, Gourmet Vanilla | 25g… at #4. Overall it ranks #55 of 935 brands.
6. Transparent Labs
~$1.4M/mo est. revenue (4% of this list) and ~21.6K units/mo from 1 product; best position #5. Its highest-ranked product here is Transparent Labs Grass-Fed Whey Protein - 30 Servings, French Vanilla… at #5. Overall it ranks #32 of 935 brands.
7. NAKED
~$1.3M/mo est. revenue (4% of this list) and ~20.8K units/mo from 3 products; best position #6. Its highest-ranked product here is NAKED Whey 2LB 100% Grass Fed Whey Protein Powder - Only 1 Ingredient… at #6. Overall it ranks #29 of 935 brands.
8. Nutricost
~$1.2M/mo est. revenue (4% of this list) and ~16.4K units/mo from 2 products; best position #25. Its highest-ranked product here is Nutricost Whey Protein Concentrate Powder (Unflavored) 2LBS, Gluten Free… at #25. Overall it ranks #2 of 935 brands.
9. Muscle Milk
~$1.1M/mo est. revenue (4% of this list) and ~45.5K units/mo from 4 products; best position #11. Its highest-ranked product here is Muscle Milk Pro Liquid High Protein Shake, Chocolate, 11 Fl Oz (Pack of 12)… at #11. Overall it ranks #56 of 935 brands.
10. Ascent
~$1M/mo est. revenue (3% of this list) and ~11.5K units/mo from 1 product; best position #22. Its highest-ranked product here is Ascent 100% Whey, Native Whey Protein Blend - Clean Post Workout Recovery… at #22. Overall it ranks #111 of 935 brands.
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Full Protein ranking
All 56 brands in the list, ordered by rank strength, plus the top 10 products.
See all Protein brands →