Top 10 prebiotics brands on Amazon (estimated revenue)

Ranked by estimated monthly revenue from Amazon's Prebiotics Best Sellers top 100. Updated October 15, 2026.

Physician's CHOICE is the top-selling prebiotics brand on Amazon by estimated revenue, at about $1.6M/mo from 3 products in the Prebiotics Best Sellers top 100. That is about 52% more than #2 Metamucil (~$1M/mo). The list is fragmented: the top 3 brands take about 23% of its estimated sales and the top 10 about 50%, spread across 65 brands in total. About 17% of the products are gummies. All figures are modeled estimates, not Amazon data.

#BrandEst. revenue/moShare of listEst. units/moProductsBest rank
1Physician's CHOICE10% share · best #1$1.6M10%61.6K3#1
2Metamucil7% share · best #2$1M7%43.7K1#2
3ProMix6% share · best #6$911K6%15.4K1#6
4Align6% share · best #14$869K6%28.8K4#14
5Lemme4% share · best #5$685K4%22.9K2#5
6Wholesome Wellness4% share · best #9$588K4%21.7K2#9
7Ritual4% share · best #12$570K4%9.5K1#12
8Benefiber3% share · best #4$539K3%33.1K2#4
9Gundry3% share · best #17$514K3%7.4K1#17
10Jarrow Formulas3% share · best #21$482K3%11K2#21
Estimates, not Amazon data. Modeled from public Best Sellers ranks and list prices; not profit. How it works

The top 10, brand by brand

1. Physician's CHOICE

~$1.6M/mo est. revenue (10% of this list) and ~61.6K units/mo from 3 products; best position #1. Its highest-ranked product here is Physician's CHOICE Probiotics for Women - PH Balance, Digestive, UT, & Feminine… at #1. Overall it ranks #37 of 3,479 brands.

2. Metamucil

~$1M/mo est. revenue (7% of this list) and ~43.7K units/mo from 1 product; best position #2. Its highest-ranked product here is Metamucil Fiber Gummies for Adults, No Sugar Added Orange Flavor, 5g Prebiotic… at #2. Overall it ranks #45 of 3,479 brands.

3. ProMix

~$911K/mo est. revenue (6% of this list) and ~15.4K units/mo from 1 product; best position #6. Its highest-ranked product here is Promix Nutrition Debloat Powder for Gut Health, Reduces Bloating, 30ct… at #6. Overall it ranks #220 of 3,479 brands.

4. Align

~$869K/mo est. revenue (6% of this list) and ~28.8K units/mo from 4 products; best position #14. Its highest-ranked product here is Align Dualbiotic, Prebiotics and Probiotics for Women and Men, Probiotics for… at #14. Overall it ranks #135 of 3,479 brands.

5. Lemme

~$685K/mo est. revenue (4% of this list) and ~22.9K units/mo from 2 products; best position #5. Its highest-ranked product here is Lemme Debloat Digestive & Gut Health Gummies, 30-Day Supply | 2 Clinically… at #5. Overall it ranks #46 of 3,479 brands.

6. Wholesome Wellness

~$588K/mo est. revenue (4% of this list) and ~21.7K units/mo from 2 products; best position #9. Its highest-ranked product here is Wholesome Wellness Dr. Formulated Raw Probiotics for Women 100 Billion CFUs… at #9. Overall it ranks #187 of 3,479 brands.

7. Ritual

~$570K/mo est. revenue (4% of this list) and ~9.5K units/mo from 1 product; best position #12. Its highest-ranked product here is Ritual Synbiotic+ 3-in-1 Probiotic Supplement - 30 Capsules - 30 Servings… at #12. Overall it ranks #67 of 3,479 brands.

8. Benefiber

~$539K/mo est. revenue (3% of this list) and ~33.1K units/mo from 2 products; best position #4. Its highest-ranked product here is Benefiber Prebiotic Fiber Supplement Gummies, Assorted Fruit Flavor, 81 Ct… at #4. Overall it ranks #113 of 3,479 brands.

9. Gundry

~$514K/mo est. revenue (3% of this list) and ~7.4K units/mo from 1 product; best position #17. Its highest-ranked product here is Gundry MD Bio Complete 3, 3-in-1 Probiotics, Pre & Postbiotics, 30 Servings… at #17. Overall it ranks #1064 of 3,479 brands.

10. Jarrow Formulas

~$482K/mo est. revenue (3% of this list) and ~11K units/mo from 2 products; best position #21. Its highest-ranked product here is Jarrow Formulas Lactoferrin Supplements 250 mg - Immune-Supporting Glycoprotein… at #21. Overall it ranks #32 of 3,479 brands.

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