Best-selling detox & cleanse brands on Amazon

60 brands have products in the Amazon Best Sellers top 100 for Detox & Cleanse. Ordered by how strongly each brand ranks in this list (higher positions and more products count more). List as of October 15, 2026.

Est. revenue/mo, top 100$15.8M
Brands in top 10060
Category leaderNature's Truth~$132K/mo est.
#1 productSerene Herbs$3M/mo est.
#BrandBest rankProductsEst. units/moEst. revenue/moOverall score
1Nature's TruthBest #19 · 2 products#19210.5K$132K63.0
2Renew LifeBest #16 · 2 products#16210.3K$193K48.2
3Global HealingBest #3 · 2 products#3224.9K$897K52.1
4Serene HerbsBest #1 · 2 products#1277.1K$3.1M51.6
5nbpureBest #2 · 1 product#2130K$838K44.9
6Dr. TobiasBest #4 · 1 product#4118.5K$369K46.5
7MilaBest #7 · 1 product#7112.5K$249K43.4
8BioteBest #8 · 1 product#8111.4K$659K41.7
9VINATURABest #9 · 1 product#9110.5K$199K46.4
10InnoSuppsBest #10 · 1 product#1019.7K$379K40.7
11JSHealthBest #11 · 1 product#1119.1K$354K40.9
12NutramaxBest #12 · 1 product#1218.6K$565K47.8
13ResciencyBest #14 · 1 product#1417.7K$144K38.1
14BellaBest #17 · 1 product#1716.7K$188K39.2
15AKKABest #21 · 1 product#2115.8K$370K36.1
16JoySpringBest #22 · 1 product#2215.6K$196K45.1
17BRAGGBest #23 · 1 product#2315.4K$189K46.4
18HyleysBest #25 · 1 product#2515.1K$49K35.5
19LymphoriaBest #26 · 1 product#2615K$265K44.7
20THORNEBest #27 · 1 product#2714.8K$131K78.0
21BiocidinBest #28 · 1 product#2814.7K$163K38.6
22Purely InspiredBest #29 · 1 product#2914.6K$46K43.7
23NatureWiseBest #31 · 1 product#3114.4K$70K64.9
24NutricostBest #37 · 2 products#3725.9K$86K97.0
25VEVBest #34 · 1 product#3414.1K$82K52.3
26Eu NaturalBest #39 · 1 product#3913.7K$191K45.6
27Nature's BountyBest #40 · 1 product#4013.7K$31K79.4
28AmenazelBest #43 · 1 product#4313.5K$115K33.8
29HesperilyntisBest #45 · 1 product#4513.4K$92K33.6
30NOQONMEBest #46 · 1 product#4613.3K$33K33.5
31TAOTERSBest #49 · 1 product#4913.2K$54K33.3
32CandiBest #51 · 1 product#5113.1K$59K33.2
33NutriFlairBest #53 · 1 product#5313K$60K46.6
34BodyBioBest #54 · 1 product#5413K$179K47.1
35HimalayaBest #56 · 1 product#5612.9K$145K62.2
36HorbäachBest #58 · 1 product#5812.8K$20K79.4
37FANSHIBest #60 · 1 product#6012.8K$43K40.9
38LULUTOXBest #65 · 1 product#6512.6K$73K32.4
39Webber NaturalsBest #81 · 2 products#8124.4K$88K34.5
40HUMBest #66 · 1 product#6612.6K$70K46.3
41DobekoBest #67 · 1 product#6712.6K$26K40.0
42WellPathBest #68 · 1 product#6812.5K$51K35.2
43HerbtonicsBest #69 · 1 product#6912.5K$50K51.2
44Dr. Schulze'sBest #70 · 1 product#7012.5K$65K32.1
45Applied NutritionBest #71 · 1 product#7112.5K$62K41.7
46Pure EncapsulationsBest #72 · 1 product#7212.4K$151K81.6
47DetoxifyBest #73 · 1 product#7312.4K$58K31.9
48UMZUBest #74 · 1 product#7412.4K$82K38.8
49ZahlerBest #76 · 1 product#7612.4K$12K46.0
50Amazing GrassBest #79 · 1 product#7912.3K$61K50.8
51IsagenixBest #80 · 1 product#8012.3K$61K39.9
52ixarcoBest #82 · 1 product#8212.2K$89K39.3
53Uncle Lee'sBest #87 · 2 products#8724.1K$44K33.9
54Doctor's BestBest #84 · 1 product#8412.2K$22K65.1
55NUTRALIVERBest #86 · 1 product#8612.2K$26K31.3
56NutriveinBest #90 · 1 product#9012.1K$42K41.3
57NOW FoodsBest #91 · 1 product#9112.1K$18K99.5
58PaulinaBest #94 · 1 product#9412K$80K30.8
59RhytherolixianBest #99 · 1 product#9912K$49K30.5
60NEWVITABest #100 · 1 product#10011.9K$48K43.8

Top 10 Detox & Cleanse products

#ProductBrandEst. revenue/mo
1Serene Herbs Soursop Bitters, Herbal Liquid with Soursop Leaf, 16 fl oz
Serene Herbs
Serene Herbs$3M
2nbpure MagO7 - Natural Colon Cleanse & Detox | Occasional Constipation Relief, Stool…
nbpure
nbpure$838K
3Global Healing Oxy-Powder Colon Cleanse, Magnesium Oxide, 60 Capsules | Gentle overnight…
Global Healing
Global Healing$676K
4Dr. Tobias Colon 14 Day Cleanse | Supports Digestion & Gut Health | Colon Cleanse Detox…
Dr. Tobias
Dr. Tobias$369K
5Colon Cleanser Detox for Weight Flush - 15 Day Intestinal Cleanse Pills & Probiotic…
Brand unconfirmed
—$157K
618-in-1 Wormwood Black Walnut Clove Herbal Cleanse Supplement |300 Softgels | Digestive &…
Brand unconfirmed
—$306K
7Mila Miamor 15 Day Cleanse - Gut and Colon Support - Advanced Gut Cleanse Detox for Women…
Mila
Mila$249K
8Biote Nutraceuticals DIM SGS | Hormone & Detox Support | 60 Capsules | 150 mg of DIM…
Biote
Biote$659K
9VINATURA Wormwood Black Walnut Clove Capsules - Cleanse, Detox, Intestinal Guard Formula…
VINATURA
VINATURA$199K
10InnoSupps Inno Cleanse 2X 14 Day Colon Cleanse & Detox Flush, 4 Week Supply | Waist…
InnoSupps
InnoSupps$379K

As an Amazon Associate, SuppRanked earns from qualifying purchases.

Estimates, not official Amazon data. Rankings and revenue are modeled from public Amazon Best Sellers lists and list prices (units × price, before returns, discounts and fees; not profit) and may differ from real sales. How it works.

Explore more

Top 10 Detox & Cleanse brands by revenue

Serene Herbs, Global Healing, nbpure and seven more, with each brand's estimated revenue share.

See the top 10 →

Head-to-head comparisons

Related categories

Detox & Cleanse brands on Amazon: FAQ

What is the best-selling detox & cleanse brand on Amazon?

By estimated revenue, Serene Herbs is the best-selling detox & cleanse brand on Amazon right now, at roughly $3.1M/mo from 2 products in the Detox & Cleanse Best Sellers top 100 (best position #1). These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

What is the #1 best-selling detox & cleanse product on Amazon?

On October 15, 2026 the #1 product in Amazon's Detox & Cleanse Best Sellers list was Serene Herbs Soursop Bitters, Herbal Liquid with Soursop Leaf, 16 fl oz from Serene Herbs, with an estimated 75.2K units and ~$3M in revenue per month. Ranks change hourly, so check Amazon for the live list.

How many detox & cleanse brands are in Amazon's top 100?

60 distinct brands have at least one product in the Detox & Cleanse top 100. The 10 biggest by estimated revenue account for about 63% of the list's estimated sales, and the top 3 for about 39%.

How much do the top detox & cleanse products sell on Amazon?

We estimate the top 100 detox & cleanse products together bring in about $15.8M a month at list price, before returns, discounts and fees. Treat it as an order-of-magnitude figure. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

How are these rankings calculated?

We read the public Amazon Best Sellers list daily, match each product to its brand, estimate monthly units from Amazon's “bought in past month” badges and sales-rank curves, and multiply by list price. Full details are on the methodology page.

SponsorYour brand here

Reach the supplement founders, operators and investors who check where they rank. $499/mo, 20/20 spots open.

Advertise on SuppRanked →

Other categories

Vitamins, Minerals & SupplementsDiet & Sports NutritionSports NutritionHerbal SupplementsVitaminsAmino AcidsAntioxidantsVitamin BEssential Fatty AcidsProteinMineralsDigestive SupplementsCollagenWeight GainersCreatineWeight LossProbioticsDiet Kits & SystemsGlandular ExtractsMagnesiumColloidal GoldEndurance & EnergyWeight Loss SupplementsEnzymesAcidophilus7-KetoProtein BlendsBlended Vitamin & Mineral SupplementsWhey ProteinPolyphenolsMultivitaminsEnergy ShotsPrenatal VitaminsFruit ExtractsB7 (Biotin)Chondroitin & GlucosaminePlant ProteinColloidal MineralsKava KavaFrench Maritime Pine Bark ExtractAll 229 categories →