Best-selling whey protein brands on Amazon

By estimated revenue, Optimum Nutrition is the best-selling whey protein brand on Amazon right now, at roughly $2.2M/mo from 5 products in the Whey Protein Best Sellers top 100 (best position #1). By estimated units, Isopure sells the most, about 41.2K a month, usually at a lower price per unit. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

On October 15, 2026 the #1 product in Amazon's Whey Protein Best Sellers list was Optimum Nutrition Gold Standard Whey Protein Powder, Vanilla Ice Cream, 2LB | 24g 100% Whey Protein… from Optimum Nutrition, with an estimated 32.5K units and ~$1.6M in revenue per month. Ranks change hourly, so check Amazon for the live list.

63 distinct brands have at least one product in the Whey Protein top 100. The 10 biggest by estimated revenue account for about 54% of the list's estimated sales, and the top 3 for about 24%.

We estimate the top 100 whey protein products together bring in about $24.4M a month at list price, before returns, discounts and fees. Treat it as an order-of-magnitude figure. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

We read the public Amazon Best Sellers list daily, match each product to its brand, estimate monthly units from Amazon's “bought in past month” badges and sales-rank curves, and multiply by list price. Full details are on the methodology page.