SuppRankedTop 10 detox & cleanse brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Detox & Cleanse Best Sellers top 100. Updated October 15, 2026.
Serene Herbs is the top-selling detox & cleanse brand on Amazon by estimated revenue, at about $3.1M/mo from 2 products in the Detox & Cleanse Best Sellers top 100. That is about 3.4× as much as #2 Global Healing (~$897K/mo). The list is fairly concentrated: the top 3 brands take about 39% of its estimated sales and the top 10 about 63%, spread across 60 brands in total. About 6% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Serene Herbs25% share · best #1 | $3.1M |
| 2 | Global Healing7% share · best #3 | $897K |
| 3 | nbpure7% share · best #2 | $838K |
| 4 | Biote5% share · best #8 | $659K |
| 5 | Nutramax5% share · best #12 | $565K |
| 6 | InnoSupps3% share · best #10 | $379K |
| 7 | AKKA3% share · best #21 | $370K |
| 8 | Dr. Tobias3% share · best #4 | $369K |
| 9 | JSHealth3% share · best #11 | $354K |
| 10 | Lymphoria2% share · best #26 | $265K |
The top 10, brand by brand
1. Serene Herbs
~$3.1M/mo est. revenue (25% of this list) and ~77.1K units/mo from 2 products; best position #1. Its highest-ranked product here is Serene Herbs Soursop Bitters, Herbal Liquid with Soursop Leaf, 16 fl oz at #1. Overall it ranks #137 of 3,479 brands.
2. Global Healing
~$897K/mo est. revenue (7% of this list) and ~24.9K units/mo from 2 products; best position #3. Its highest-ranked product here is Global Healing Oxy-Powder Colon Cleanse, Magnesium Oxide, 60 Capsules | Gentle… at #3. Overall it ranks #128 of 3,479 brands.
3. nbpure
~$838K/mo est. revenue (7% of this list) and ~30K units/mo from 1 product; best position #2. Its highest-ranked product here is nbpure MagO7 - Natural Colon Cleanse & Detox | Occasional Constipation Relief… at #2. Overall it ranks #405 of 3,479 brands.
4. Biote
~$659K/mo est. revenue (5% of this list) and ~11.4K units/mo from 1 product; best position #8. Its highest-ranked product here is Biote Nutraceuticals DIM SGS | Hormone & Detox Support | 60 Capsules | 150 mg… at #8. Overall it ranks #675 of 3,479 brands.
5. Nutramax
~$565K/mo est. revenue (5% of this list) and ~8.6K units/mo from 1 product; best position #12. Its highest-ranked product here is Nutramax Avmacol Extra Strength Sulforaphane Producing Supplement, 75 Tabs… at #12. Overall it ranks #261 of 3,479 brands.
6. InnoSupps
~$379K/mo est. revenue (3% of this list) and ~9.7K units/mo from 1 product; best position #10. Its highest-ranked product here is InnoSupps Inno Cleanse 2X 14 Day Colon Cleanse & Detox Flush, 4 Week Supply… at #10. Overall it ranks #796 of 3,479 brands.
7. AKKA
~$370K/mo est. revenue (3% of this list) and ~5.8K units/mo from 1 product; best position #21. Its highest-ranked product here is AKKA Akkermansia Probiotic, Liver Health, Digestion & Metabolism, 60 Caps… at #21. Overall it ranks #1508 of 3,479 brands.
8. Dr. Tobias
~$369K/mo est. revenue (3% of this list) and ~18.5K units/mo from 1 product; best position #4. Its highest-ranked product here is Dr. Tobias Colon 14 Day Cleanse | Supports Digestion & Gut Health | Colon… at #4. Overall it ranks #317 of 3,479 brands.
9. JSHealth
~$354K/mo est. revenue (3% of this list) and ~9.1K units/mo from 1 product; best position #11. Its highest-ranked product here is JSHealth Detox + Debloat. Bloating Relief for Women, 60 Tablets… at #11. Overall it ranks #771 of 3,479 brands.
10. Lymphoria
~$265K/mo est. revenue (2% of this list) and ~5K units/mo from 1 product; best position #26. Its highest-ranked product here is Lymphoria Lymphatic Drainage Drops for Bloat Relief & De-Puff – Cleavers, Red… at #26. Overall it ranks #419 of 3,479 brands.
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Full Detox & Cleanse ranking
All 60 brands in the list, ordered by rank strength, plus the top 10 products.
See all Detox & Cleanse brands →